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Obesity phenotypes and subclinical cardiovascular diseases in a mixed‐ancestry South African population: A cross‐sectional study (南非混合血统人群的肥胖表型与亚临床心血管疾病:一项横向研究)

journal contribution
posted on 19.07.2019 by Tandi Edith Matsha-Erasmus, Maria Diana Hartnick, Yogan Kisten, Rajiv T. Eramus, Andre P. Kengne
Efforts to characterize the disease risk associated withobesity1suggest that related metabolic abnormalitiesare not uniform in all obese persons. The conceptsof“metabolically-healthy-”and“metabolically-abnormal-” normal-weight, overweight and obese havebeen used to characterize the phenotypes resulting fromthe cross-classification of individuals by body mass index(BMI) and metabolic status.2Studies, mostly from devel-oped countries, suggest each phenotype to represent asizable proportion of the population. However, evidenceon their association with cardiovascular disease (CVD)risk is inconclusive, and no study has assessed the preva-lence of obesity phenotypes and correlation with diseaserisk in Africans.3We assessed the prevalence of obesityphenotypes, and their association with sub-clinical CVDin mixed-ancestry South Africans